HATU;O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Hexafluorophosphate

HATU is a premium-grade coupling reagent widely utilized in solid-phase peptide synthesis (SPPS) and organic chemistry for its exceptional efficiency in forming amide bonds. As a uronium-type activator, it minimizes racemization and ensures high-yield reactions, making it a staple in pharmaceutical manufacturing, bioconjugation, and advanced molecular research.

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Product Introduction

Catalog	BCC-002
Product Name	HATU;O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
CAS	148893-10-1
EINECS	604-662-7
Molecular Formula	C₁₀H₁₅F₆N₆OP
Molecular Weight	380.23
Appearance	White or pale yellow crystalline powder
Assay	≥99.0%
Water	≤0.30%
Melting Point	183-191℃
Molecular structure

Introduction

Key Features

High Reactivity

Accelerates amide/peptide bond formation under mild conditions.

Low Epimerization

Ideal for synthesizing stereochemically sensitive compounds.

Pharmaceutical Grade

≥99% purity (HPLC), optimized for critical applications.

Broad Compatibility

Works effectively with Fmoc/t-Boc protection strategies.

Applications

Peptide & oligonucleotide synthesis.
Preparation of antibody-drug conjugates (ADCs) and PROTACs.
Medicinal chemistry and high-throughput screening (HTS).

Packaging: Provide packaging in various specifications. Store at 4°C in a dry environment.

Why Choose Us

Batch-specific certificates of analysis (COA) provided.
Customizable packaging and technical support.
Globally compliant with REACH, ISO 9001, and GMP guidelines.

Feel free to consult us at any time for a quotation.

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